Empty gravity flow nucleic acid purification columns are designed for packing ion exchange resin to extract and purify nucleic acids, which are supplied with tubes and hydrophilic frits. Extracted plasmid is ready to use in many downstream applications, including restriction digestion, ligation and transformation, PCR, sequencing and library construction.

Since analyses and tests are usually time-consuming and costly, obtaining reliable, accurate, and trustworthy results has always concerned laboratory technicians. Therefore, many laboratory protocols and procedures have recommended filter-equipped sample holders.